AI-powered peptide intelligence by Framework Island. Evidence-based, editorially rigorous, and committed to transparency in peptide science.
GLP-1
Two injectable medications are reshaping obesity medicine: tirzepatide (Mounjaro/Zepbound) and semaglutide (Ozempic/Wegovy). Both belong to the GLP-1 drug class, both are once-weekly injections, and both produce clinically meaningful weight loss. But the similarities mostly end there. In May 2025, the landmark SURMOUNT-5 trial published in the New England
GLP-1
Peptides
PT-141 (bremelanotide) is the only FDA-approved peptide that works through the brain — not blood flow — to restore sexual desire in both men and women. Here's everything you need to know.
Peptides
BPC-157 has quietly become one of the most talked-about peptides in recovery circles, functional medicine clinics, and biohacking communities worldwide. Derived from a naturally occurring protein in gastric juice, this 15-amino-acid chain has demonstrated remarkable healing properties across dozens of preclinical studies — and as of early 2026, it received a
GLP-1
Cagrilintide & CagriSema: The Amylin+GLP-1 Combo Redefining Weight Loss (2026 Guide) For years, GLP-1 receptor agonists like semaglutide and tirzepatide dominated the conversation around obesity medicine. But a new class of combination therapy is forcing experts to rethink what's possible in weight loss pharmacology. CagriSema — a once-weekly
Peptides
TB-500 is one of the most systemically active healing peptides in research. Learn how it works, what the science shows, how to stack it with BPC-157, and what dosing protocols look like in 2026.
GLP-1
Semaglutide reduced body weight by nearly 15% in clinical trials and cut cardiovascular events by 20% in people with obesity and no diabetes. Here is the complete science-backed guide to Ozempic, Wegovy, and Rybelsus in 2026.
Peptides
What Is the CJC-1295 + Ipamorelin Stack? The CJC-1295 and ipamorelin stack is one of the most widely used peptide combinations in modern anti-aging and performance medicine. These two peptides work through distinct but complementary mechanisms to amplify the body's natural growth hormone (GH) output — without the side effect
Peptides
What Is Epithalon? Epithalon (also spelled Epitalon or Epithalone) is a synthetic tetrapeptide composed of four amino acids: alanine, glutamic acid, aspartic acid, and glycine (Ala-Glu-Asp-Gly, or AEDG). It was first developed in the 1980s by Professor Vladimir Khavinson and his team at the Saint Petersburg Institute of Bioregulation and
Peptides
Selank is a synthetic heptapeptide anxiolytic developed in Russia that has attracted serious scientific attention for one unusual reason: it delivers anti-anxiety effects comparable to benzodiazepines — without the sedation, cognitive blunting, dependence, or withdrawal that define that drug class. For anyone who has struggled with anxiety or wanted to optimize
Peptides
Epithalon — also spelled Epitalon — is one of the most extensively researched anti-aging peptides in modern gerontology. A synthetic tetrapeptide composed of four amino acids (alanine-glutamic acid-aspartic acid-glycine, or AEDG), Epithalon was developed by Russian scientist Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology starting in the late
Peptides
Selank (TKPRPGP) is a Russian-developed synthetic peptide with proven anxiolytic effects, BDNF modulation, and a safety profile that outperforms benzodiazepines. Here's the complete science-backed guide.